topA

topA
3A

DNA topoisomerase I

locus
JCVISYN3A_0859
Molecular weight
75.00 kDa
pI
8.76
Protein length
Gene length
function
relaxation of negatively supercoiled DNA behind RNA polymerase
product
DNA topoisomerase I
essential
Quasi essential

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

Gene
Coordinates
518165 - 520126 (+)
The protein
Catalyzed reaction/ biological activity
DNA topology
Structure
[PDB|6OZW] (from Streptococcus mutans, 32% identity) [pubmed|31204053]
[AF|Q6MS50]
Expression and Regulation
additional information
Early Growth Phase: proteins per cell: 176 [pubmed|30657448]
References
Reviews
6305585,16936698,29177730
Original publications
27013737,31204053,9722641,28414321,26490962,25232096,23514156,22923519,10713132,12167668,30222737,30957856,30478267,32232337

97ca9883edd396863d2bad638fb0dfeb279789fa

Page visits: 146

Time of last update: 2025-07-15 05:11:50

Author of last update: TiagoPedreira