parC

parC
3A

subunit A of DNA topoisomerase IV

locus
JCVISYN3A_0453
Molecular weight
102.38 kDa
pI
7.15
Protein length
Gene length
function
chromosome segregation and compaction
product
DNA topoisomerase IV subunit A
essential
Essential

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

Gene
Coordinates
304191 - 306887 (+)
The protein
Catalyzed reaction/ biological activity
ATP-dependent breakage, passage and rejoining of double-stranded DNA (according to UniProt)
Structure
[PDB|4I3H] (the [protein|2c7265dce5f96121787916302ca0e5a375e13bcd|parE]-[protein|5061acd93483948ee961d87cfbbe06104779b280|parC] complex from Streptococcus pneumoniae, 55% identity) [pubmed|23965305]
[AF|Q6MT97]
Expression and Regulation
additional information
Early Growth Phase: proteins per cell: 156 [pubmed|30657448]
References
Reviews
16936698
Original publications
27013737,23965305,16272394,9539793,16267290,23965305,9334322,8940171,7590259,12857958,11090135,8227000

5061acd93483948ee961d87cfbbe06104779b280

Page visits: 155

Time of last update: 2025-06-21 17:13:15

Author of last update: TiagoPedreira